

ETS surgery is a surgical treatment that may be considered in selected patients with severe primary hyperhidrosis, particularly excessive sweating of the hands.
ETS stands for “Endoscopic Thoracic Sympathectomy.” The procedure aims to interrupt specific parts of the sympathetic nerve pathway inside the chest that contribute to excessive sweating.
After ETS, sweating of the hands may decrease significantly. However, the most important issue is not only whether hand sweating improves. Increased sweating in other parts of the body, known as compensatory sweating, is one of the main long-term effects discussed before surgery.
For this reason, ETS is not a first-line treatment for every person with excessive sweating. The type and severity of hyperhidrosis, its impact on daily life, previous treatments, and the possible long-term consequences of surgery should all be considered.
Sweat glands are controlled by the autonomic nervous system.
The sympathetic nervous system sends signals that stimulate sweating.
In primary focal hyperhidrosis, this system may become excessively active in certain areas, leading to sweating beyond what is required for normal temperature regulation.
Commonly affected areas include:
During ETS, the sympathetic chain inside the chest is interrupted at a selected level.
The aim is to reduce excessive nerve signals reaching the targeted sweating area.
The term ETS is often used broadly.
Technically, different methods may be used to interrupt the sympathetic pathway.
In a sympathectomy, a segment of the sympathetic chain may be removed.
In a sympathotomy, the nerve pathway is divided at a specific level.
Some techniques may also use clips.
The exact method depends on the surgical approach.
None of these techniques should be assumed to be fully reversible.
The strongest indication for ETS is severe primary palmar hyperhidrosis, meaning excessive sweating of the hands.
Surgery may be considered in selected patients whose hands are frequently or constantly wet and who experience problems such as:
However, inconvenience alone is not enough to justify surgery.
The severity of symptoms and overall effect on quality of life should be considered.
Primary hyperhidrosis is excessive sweating that occurs without another disease or medication causing it.
It often:
The hands, feet, underarms, and face are commonly affected.
Before considering ETS, it is important to determine whether the sweating is primary or secondary to another medical condition.
Usually not.
Secondary hyperhidrosis may develop because of another medical condition, hormonal change, or medication.
Possible causes include:
Sweating that begins suddenly, affects the whole body, or is associated with significant night sweats may require investigation for an underlying cause.
In these cases, treatment should generally focus on the underlying condition rather than interruption of the sympathetic nerve pathway.
ETS is not suitable for every patient with hyperhidrosis.
It may be considered particularly in patients who:
The decision is based not only on the amount of sweating, but also on how significantly the condition affects quality of life.
ETS is generally not the first treatment for palmar hyperhidrosis.
Depending on the patient, treatment options may include:
ETS may become an option when severe primary palmar hyperhidrosis persists despite appropriate non-surgical treatment or when these treatments are not sustainable.
ETS may reduce axillary sweating in some patients, but surgery is approached more cautiously when excessive sweating is limited to the underarms.
This is partly because several other treatment options are available, including:
Outcomes of ETS for palmar sweating are generally more predictable than for isolated axillary hyperhidrosis.
For this reason, ETS is not usually the first choice for underarm sweating alone.
ETS does not directly target the sympathetic pathways responsible for sweating of the feet.
Some patients may notice reduced foot sweating after surgery for palmar hyperhidrosis, but this cannot be predicted or guaranteed.
Thoracic sympathectomy is not a standard treatment performed solely for plantar hyperhidrosis.
Options such as iontophoresis, topical treatments, and other non-surgical methods may be considered first.
ETS may be considered in selected patients with severe primary craniofacial hyperhidrosis.
However, results may be less predictable than in palmar hyperhidrosis, and the risk of compensatory sweating remains important.
For this reason, surgery for facial and scalp sweating is usually considered only after appropriate non-surgical options and careful patient selection.
Facial blushing and excessive sweating may occur together but are not the same condition.
Sympathetic surgery has historically been used in selected patients with severe facial blushing that significantly affects daily life.
However, the balance between potential benefit and long-term effects is more controversial than in severe palmar hyperhidrosis.
The possibility of compensatory sweating and the permanent nature of some surgical effects should be discussed carefully.
Treatment depends on the area affected.
Possible options include:
Products containing aluminum salts may be used particularly in mild or moderate hyperhidrosis.
Iontophoresis is commonly used for excessive sweating of the hands and feet.
The hands or feet are placed in water while a low electrical current is applied with the aim of reducing sweat gland activity.
Botulinum toxin temporarily reduces nerve signals to the sweat glands.
It may be used for the underarms, hands, and selected other areas.
Anticholinergic medications may reduce sweating in some patients.
Possible side effects may include:
The treatment sequence should be individualized according to the sweating pattern and the patient’s overall health.
ETS is performed under general anesthesia.
It is usually carried out using a minimally invasive thoracoscopic approach.
Small incisions are made on the side of the chest.
Through these incisions, the surgeon introduces:
The sympathetic chain is identified along the inner surface of the chest wall.
The selected level is then interrupted according to the surgical plan.
This may involve cutting, cauterizing, or another method of interruption.
The procedure is generally performed on both sides.
The sympathetic chain runs along both sides of the spine inside the chest.
Different nerve levels contribute to sweating in different areas of the body.
For this reason, the level selected for surgery depends on the pattern of hyperhidrosis.
The surgical level may influence both the effectiveness of sweating control and the risk of side effects.
There is no single level used for every patient.
The selected level may vary according to whether the patient has:
Modern surgical descriptions may identify the level according to the ribs rather than older ganglion-based terminology.
More extensive or higher interruption may be associated with a different side-effect profile, which is one reason careful surgical planning is important.
The duration varies according to anatomy and surgical technique.
Factors that may influence operating time include:
There is no single fixed duration that applies to every patient.
Some patients may be discharged after a relatively short postoperative period following minimally invasive ETS.
The length of stay depends on factors such as:
Recovery is not identical for every patient.
Changes in hand sweating may be noticed soon after surgery.
However, the overall pattern of sweating can continue to change during the postoperative period.
Completely dry hands are not always considered an ideal outcome, as some patients may experience excessive dryness.
Long-term assessment should include not only hand sweating but also changes in sweating elsewhere in the body.
Compensatory sweating refers to increased sweating in areas that were not previously a major problem.
Common areas include:
The severity varies greatly.
In some patients it is mild and manageable.
In others, it may become a significant problem affecting daily life.
Compensatory sweating is one of the most important issues in the decision-making process before ETS.
The operation may reduce hand sweating while increasing sweating in other areas.
This may become particularly noticeable:
It is not possible to predict with certainty who will develop severe compensatory sweating.
For this reason, patients should understand this possibility before making a surgical decision.
Yes.
In some people, compensatory sweating may become less noticeable over time.
However, it does not disappear in every patient.
It can continue for years and may become a long-term or permanent issue.
Therefore, the long-term redistribution of sweating should be considered when evaluating the risks and benefits of ETS.
The exact mechanism of compensatory sweating is not completely understood.
It is thought to involve changes in how the autonomic nervous system regulates body temperature after interruption of the sympathetic pathway.
The common explanation that “the sweat from the hands simply comes out somewhere else” is an oversimplification.
Sweating regulation involves more complex neurological and thermoregulatory mechanisms.
As with any operation, ETS carries potential risks.
These may include:
Horner syndrome is a rare but important neurological complication related to injury of the upper sympathetic pathway.
The risk profile depends partly on the surgical level and technique.
Horner syndrome can occur when sympathetic nerves supplying the eye and face are affected.
Possible signs include:
Modern surgical planning aims to reduce this risk by avoiding unnecessary intervention at higher sympathetic levels.
However, the risk is not completely zero.
Gustatory sweating refers to sweating of the face or scalp triggered by eating, particularly certain foods.
It may develop in some patients after ETS.
The severity varies between individuals.
The sympathetic nervous system also contributes to regulation of heart rate.
Interruption at certain levels may influence resting or exercise heart rate in some patients.
Most patients do not develop a clinically important problem, but people with pre-existing rhythm disorders or significant bradycardia may require additional assessment before surgery.
ETS should not be regarded as a reliably reversible procedure.
If the nerve has been cut or removed, the effect may be permanent.
In clipping procedures, the clip can theoretically be removed.
However, removing the clip does not guarantee that nerve function or the previous sweating pattern will return.
The decision to undergo ETS should therefore not be approached as if it were a temporary trial.
Some techniques compress the sympathetic chain with clips rather than cutting it.
Although the clips may later be removed, this does not guarantee full recovery of nerve function or reversal of compensatory sweating.
Changes in the nerve may become persistent over time.
Clipping should therefore not be considered a method that eliminates the long-term risks of ETS.
Yes.
Recurrence of sweating in the treated area can occur.
Possible reasons include:
Recurrence rates vary depending on the affected region and surgical technique.
ETS can provide long-term and substantial reduction in palmar sweating.
However, describing it as a “guaranteed permanent cure” would be inaccurate.
Sweating may recur in some patients, and compensatory sweating may become a new long-term problem even when hand sweating improves.
Treatment success should therefore not be judged only by whether the hands become dry.
Some patients are satisfied with the reduction in palmar sweating.
Others may be dissatisfied, particularly if they develop severe compensatory sweating.
For this reason, preoperative assessment should consider:
Realistic expectations are an important part of patient selection.
After minimally invasive surgery, patients may experience:
Early walking and movement are encouraged when clinically appropriate.
Return to daily activities depends on the patient’s recovery and the physical demands of work.
More strenuous physical activity is generally resumed gradually.
The key question is not simply whether ETS can reduce hand sweating.
The decision should balance:
ETS is therefore a procedure in which careful patient selection is as important as the operation itself.
ETS is a minimally invasive thoracic surgical procedure that interrupts selected parts of the sympathetic nerve chain to reduce excessive sweating.
Its clearest role is in severe primary palmar hyperhidrosis, particularly when appropriate non-surgical treatments have not provided sufficient benefit.
It can reduce axillary sweating in some patients, but because several local and non-surgical treatments are available, ETS is not usually the first choice for isolated underarm hyperhidrosis.
Foot sweating may improve in some patients, but this is not predictable. ETS is not routinely performed solely to treat plantar hyperhidrosis.
A reduction in palmar sweating may be noticed early after surgery. Long-term evaluation should also consider compensatory sweating and possible recurrence.
Reported rates vary according to the surgical technique and patient group. It is common, but severity differs greatly and it is not possible to predict precisely who will develop severe symptoms.
It may decrease over time in some people, but in others it may persist for years or remain permanent.
ETS should not be considered reliably reversible. Even when clips are used and later removed, return to the preoperative sweating pattern cannot be guaranteed.
Possible risks include compensatory sweating, bleeding, infection, pneumothorax, pain, excessive dryness, gustatory sweating, and rarely neurological or heart-rate-related effects.
No. The distinction between primary and secondary hyperhidrosis should first be made, severity should be assessed, and appropriate non-surgical treatments should generally be considered before surgery.
This content is intended for general informational purposes only. ETS is not a first-line or appropriate treatment for every person with excessive sweating. Surgical assessment should consider whether the hyperhidrosis is primary or secondary, which areas are affected, symptom severity, previous treatments, expected benefits, and possible long-term risks. Compensatory sweating is an important postoperative effect that may persist or become permanent in some patients. The information provided here does not replace individual medical assessment, diagnosis, or treatment planning.